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SLC7A11/xCT in Cancer: Biological Functions and Therapeutic Implications

Selon une tude ralise en mai 2020 auprs de plusieurs patients de la Covid-19, il a t dmontr que : La carence en glutathion semble tre un facteur crucial responsable des dommages oxydatifs du poumon induits par le SRAS-CoV-2 et, par consquent, conduit des manifestations graves, telles que le syndrome de dtresse respiratoire aigu, la dfaillance multiviscrale et la mort chez les patients COVID-19

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As explained below, strategies aiming at identifying physiological substrates/ligands have been recently developed for other GSTs and they should be applied to GHRs

Moreover, there is a requirement for a thorough evaluation of safety and immunogenicity for all the NP-based gene delivery systems during the clinical trials
