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Activation of the somatostatin receptor 3 (SSTR3) leads to its arrestin-dependent ubiquitination and subsequent exit (Shinde et al., 2020) while constitutive ubiquitination of SMO by the ligase WWP1 keeps ciliary SMO levels low under basal conditions (Lv et al., 2021)
Passage of inhaled particles into the blood circulation in humans
The healing was much faster than expected
Nat Med (2022) 28(10):19858
