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IsoLGs (Isolevuglandins) drive neutrophil migration in hypertension and are essential for the formation of neutrophil extracellular traps

We have co-crystallized PrfA bound to an intact 28-bp complementary dsDNA (plus 1-nt 5 overhang at either end) and solved the structure of the binary complex at 2.93 resolution (X-ray statistics in Table S1)

976 Empagliflozin, a sodium-glucose cotransporter 2 inhibitor, is a novel hypoglycemic agent that increases urinary glucose and sodium excretion
doi: 10.1089/ars.2015.6317
Proteasomal degradation is transcriptionally controlled by TCF11 via an ERAD-dependent feedback loop
