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A two-step progression from simple steatosis to steatohepatitis and fibrosis has been proposed 13 , and suggests that after fat accumulation in the liver due to insulin resistance, lipids are peroxidized with cytokines and Fas ligand induced by excessive ROS

Barde S, et al

Contact your provider for severe abdominal pain, persistent vomiting with dehydration, right-upper-quadrant pain with fever, or any allergic reaction symptom

Toxic metals and oxidative stress part I: Mechanisms involved in metal-induced oxidative damage
Neuroscience 147(3):674679
