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Fasting triglyceride levels decreased by approximately 3035% at the 12mg retatrutide dose a magnitude that significantly exceeds what is seen with semaglutide or tirzepatide at their respective maximum doses

For compounds that give negative results, the completion of either option of the standard test battery, performed and evaluated in accordance with current recommendations, will usually provide sufficient assurance of the absence of genotoxic activity and no additional tests are warranted

10.1089/ten.1999.5.127 138 TarnawskiA
