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Interactions between TRPV1 and long sustained thermal hypersensitivity in oxidative stress-induced inflammatory hyperalgesia of mouse hind paw were reported (Keeble et al., 2009)

Steindler DA, Reynolds BA

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Enhanced -secretase activity increases A production through the amyloidosis pathway (Ward et al., 2014)

Likewise, a permanent reduction of PV neuron density in anterior cingulate cortex of Gclm KO mice occurs following the administration of GBR-12909 (dopamine re-uptake inhibitor leading to excess extracellular dopamine level that generates ROS through its catabolism) during postnatal development, but not adulthood [81]