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Oxidative stress affects numerous molecular pathways, including inhibition of the cystine/glutamate antiporter system, decreased expression of GPX4, disruption of iron homeostasis and lipid peroxidation, which is a major driver of ferroptosis activation (54)

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This can be prevented by supplementing with L-glutamine, which maintains the integrity of the intestinal barrier and reduces the incidence of gut-derived infections.[108] Glutamine appears to have the most benefit when inflammation is present despite the depletion of nutritional stores.[109] It reduces inflammatory cytokine release within the bowel wall[110] and increases heat shock protein, which protects enterocytes from injury

Suda A, Umaru BA, Yamamoto Y, Shima H, Saiki Y, Pan Y, et al

Ipamorelin is a peptide analogue of ghrelin that stimulates the secretion of GH