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Chronic poor sleep adds up and leaves you with a sleep debt that you might never be able to pay back

J Am Coll Cardiol

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However, it is presently unclear whether NRF1 or other transcription factors involved in mitobiogenesis directly affect the expression of Bnip3

Risk factors include older age, gastrointestinal disorders, vegan diets, or use of certain medications like metformin or PPIs
