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Section IV

doi: 10.1056/NEJM198812293192602 145 GoldDBowdenRSixbeyJRiggsRKatonWJAshleyRet al

For example, H3K9la in recurrent GBM tissues and TMZ-resistant cells confers temozolomide (TMZ) resistance in GBM by triggering LUC7L2-mediated retention of intron 7 in MLH1, which reduces its expression and inhibits mismatch repair, ultimately contributing to TMZ resistance in GBM

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A person can train hard, look athletic, maintain low body fat, and still carry unfavorable lipid patterns that affect arterial health over years not weeks
