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Severe cases of homocystinuria are typically caused by autosomal recessive genetic defects and exhibit characteristic clinical features including ocular lens dislocation, marfanoid features and other skeletal abnormalities including osteoporosis, intellectual disability, and thromboembolic disease, the latter frequently being the cause of premature death in affected individuals (28)

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Always follow the documented dose for the specific vial being referenced, and for anything user-specific, run the numbers through the dosage calculator rather than improvising

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