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Interestingly, in renal clear cell carcinoma, IDO expressed by neovascularization endothelial cells is an inhibitory factor in tumor growth because it limits the flow of tryptophan from the blood to the tumor or produces tumor toxic substances (Riesenberg et al., 2007)
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Oxidative stress is a well-known driver of AD pathogenesis ( A critical finding of this study was the reduction of A deposition in HRW-treated zebrafish, which suggests a potential link between oxidative stress modulation and A dynamics
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Mol Neurodegener 18(1):83
