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Similar to other chronic inflammatory conditions, DNA damage due to oxidative stress caused by free radicals is thought to play a role

Percentage differences between groups were compared using the 2 test

Aromatase is an enzyme that converts testosterone to estradiol (the most potent estrogen form) and androstenedione to estrone ( The anti-estrogenic compounds mentioned in the WADA list can be divided into two groups: SERMs (bazedoxifene, clomiphene, cyclofenil, ospemifene, raloxifene, tamoxifen, and toremifene) and selective estrogen receptor degraders (SERDs), of which fulvestrant is a representative

doi: 10.1097/00000542-200601000-00022

We compared the vascular permeability on the non-ligature side and on the ligature side in each of the three groups