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It was thought that some type of receptor on the cell surface was involved but evidence was lacking for what this molecule might be and how it might work

In a disorder defined by symptoms related to fatigue, autonomic nervous system problems [e.g., ( By using brainstem-specific spatial registration in addition to standard neocortex spatial registration, neuroimaging studies of ME/CFS are much more likely to detect any functional and structural abnormalities that may be driving autonomic and neuroimmune-related symptoms
doi: 10.1186/1472-6882-9-53 39 FruscalzoA.SalmeriM

One of the most researched areas involving GHK-Cu relates to wound healing and tissue repair pathways

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