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The released TPA would then be incorporated into the host cells through the TPA transporter (PcaK) and further metabolized into protocatechuic acid (PCA) catalyzed by TPA 1,2-dioxygenase (TPADO) and 1,2-dihydroxy-3,5-cyclohexadiene-1,4-dicarboxylate dehydrogenase (DCDDH) (Figure 3)

Therefore, Fasn likely mediates the inhibitory effect of hypertension on endothelial cell proliferation in the corpus cavernosum

ML: 2.3 mm

Acetaldehyde is the major metabolite mediated through CYP2E1

Ingested fats are broken down and converted into free fatty acids, which are then stored in fat cells in a form known as triglycerides where they remain as potential energy units until called for by negative energy states