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Description
Unlike classical inflammation (characterized by heat, redness, and pain), neuroinflammation primarily involves the release of pro-inflammatory mediators (e.g., cytokines, chemokines, and ROS) by resident immune cells, particularly microglia, the CNSs innate immune effectors [110, 111]

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J Clin Invest 117 : 889901 Acknowledgements We are grateful to Dr

10.1016/j.redox.2015.11.010 131 RalserM.WamelinkM

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