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chac1 er stress glutathione degradation Human Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF/CRE Regulatory Element* A scheme of the mechanism

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Berrocal-Zaragoza MI, Murphy MM, Ceruelo S, Quadros EV, Sequeira JM, Fernandez-Ballart JD

chac1 er stress glutathione degradation Human Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF/CRE Regulatory Element* A scheme of the mechanism

USA 94 , 1321513220 (1997)

chac1 er stress glutathione degradation Human Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF/CRE Regulatory Element* A scheme of the mechanism

Contributor Information Mi Wang, Email: [email protected]

chac1 er stress glutathione degradation Human Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF/CRE Regulatory Element* A scheme of the mechanism

A methionine residue oxidizes

chac1 er stress glutathione degradation Human Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF/CRE Regulatory Element* A scheme of the mechanism

Interestingly, as desensitization involves a number of steps including receptor phosphorylation, -Arr recruitment, and internalization or degradation, aberrations at any level may precipitate disease

chac1 er stress glutathione degradation Human Protein Degrades Glutathione, and mRNA Induction Is Regulated by the Transcription Factors ATF4 and ATF3 and a Bipartite ATF/CRE Regulatory Element* A scheme of the mechanism

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