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For this purpose, we treated normal aging mice with intraperitoneal injection of FOXO4-DRI at a dose of 5 mg/kg for 1 month

Therefore, the NAC-responsive accumulation of Kyn may be particularly relevant for understanding the fundamental biology of mTORC1 activation by amino acids (Jewell et al

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In addition to its proteolytic cascades, uPAR are also involved in signaling events leading to cell proliferation, migration, angiogenesis, remodeling of the cell adhesion, cytokine release, priming of neutrophil for oxidant production and chemotaxis, all of which play a key role in the development, implantation and metastasis of tumors [88, 248]

NPJ Biofilms Microbiomes 7, 42