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Nutr J 23(1):31
Alpha-MSH analogs like Melanotan-2 are highly sensitive to physical agitation, and the peptide structure is more fragile in the transition state between dry powder and fully dissolved solution

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119 Notably, this is the only inward-open structure obtained for a MATE exporter, and structural alignments revealed that the Cl ion in MurJ is bound to an analogous location on PfMATE
