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Because 2-oxoglutarate is a dicarboxylate, it could share the dicarboxylate carrier for its mitochondrial entry
Less ATP promotes more oxidative stress, meaning cells won't have the energy they need to function optimally

doi: 10.2147/TCRM.S273700
Med Sci (Basel) 6(3):79 Chvez-Talavera O et al (2017) Bile acid control of metabolism and inflammation in obesity, type 2 diabetes, dyslipidemia, and nonalcoholic fatty liver disease
