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Indirect markers include elevated oxidative stress markers, poor recovery from exercise, chronic fatigue, weakened immune function, or elevated liver enzymes

Volumes were calculated to produce a total volume of 50 l solvent per 1 l of cell volume

Crucially, the context-dependent role of regulatory pathways like Nrf2 highlights the complexity of therapeutic targeting

Blood pressure and general status are checked

Notably, NNMT expression is upregulated in several malignancies, including kidney renal clear cell carcinoma, kidney renal papillary cell carcinoma, pancreatic adenocarcinoma, glioblastoma multiforme, sarcoma, and lymphoid neoplasm diffuse large B-cell lymphoma [29]