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Cells were first gently lysed with the cytoplasmic extraction buffer to release cytoplasmic components, and the supernatant was collected after centrifugation as the cytoplasmic protein fraction

Nature 488 , 100105 (2012)

S., Seredenina, T

It is a complex process controlled by angiogenic and angiostatic molecules resulting in ideal revascularization of the wound bed, and providing oxygen, nutrients, and inflammatory cells to the newly growing/regenerating as well as tumor tissue (20, 21)