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Rg 1 specifically upregulates activating transcription factor (ATF) 3/acyl-coenzyme A oxidase (ACOX) 2 to alleviate NAFLD, and how Rg 1 regulates NAFLD through these two genes is unknown ( 4.2.2 Oxidative stress The occurrence of OS in the body indicates that the antioxidant system scavenges ROS at a slower rate than the rate of ROS production, which is an important factor in liver injury and NAFLD progression (Kumar et al., 2021)

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