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Description
[DOI] [PMC free article] [PubMed] [Google Scholar] 69.Mancias J.D., Pontano Vaites L., Nissim S., Biancur D.E., Kim A.J., Wang X., Liu Y., Goessling W., Kimmelman A.C., Harper J.W
10.1038/ng746 Nat
Although Trx and Grx function as hydrogen donors for RNR and have the same motif in their active site, many of their functions do not overlap
Its core idea is to link drugs with molecules in biological networks (such as proteins, genes, and metabolites) to reveal the mechanisms of action of a drug and its potential side effects
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