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Neuroprotection of NRF2 against ferroptosis after traumatic brain injury in mice
Furthermore, Dihexa has neurotrophic activity seven times greater than brain-derived neurotrophic factor (BDNF)
The other dihydroperoxide products (1,3-disubstituted and 1,7-disubstituted) are created by concerted addition of singlet oxygen on monohydroperoxides
the rationale is based on the fact that improved glycemia restores sensitivity to GIP [14, 16] and peptide engineering enables the design of hybrid ligands exhibiting dual agonism, as proved in experimental studies [19]
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