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This charge-switching mechanism, exemplified by PEG- b -poly(-lysine)-hydrazone- doxorubicin micelles from the cited study, enables targeted drug delivery with improved intracellular release and reduced systemic toxicity, highlighting the therapeutic advantage of pH-sensitive hydrazone bonds in nanocarrier design [46]

doi: 10.1016/j.jtauto.2025.100316

This prevents the normal transmission of insulin signals through the PI3K-AKT pathway, ultimately leading to IR [39]

You are at an increased risk of this if you have abnormal electrolyte levels, heart rhythm problems, or are taking other medications that cause heart rhythm problems

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