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The following table summarizes common claims and their evidence basis: The key pattern: most benefits are real only for individuals who are actually deficient in B12

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HR 0.70 [95% CI 0.530.93], P = .0075) in patients with multiple myeloma with the addition of selinexor

No published data establishes an optimal rest period

Small real-world series also suggest that reduced-frequency dosing can hold a plateau