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Eukaryotic translation initiation factor 5A (eIF5A) is a highly conserved protein that contributes to the expression of various mitochondrial proteins, and some of these proteins are involved in the TCA cycle and OXPHOS

The impairment in the Krebs Cycle may induce inflammatory pathways through the promotion of mitochondrial ROS production (Fig

To confirm that the improved response to cold was dependent on creatine, mice were treated with the creatine-depleting drug -guanidinopropionic acid (-GPA) 21 , which can only be used acutely as chronic exposure can induce weight loss 19,21

Cumulative evidence from animal studies has shown because of its neuroprotective properties, HeA-enriched HEM can reduce neuronal cell death and neurological symptoms in several neurological diseases, including cerebral ischemia, AD, PD, and depression 15

Phospholipids are metabolized, utilized, or excreted