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Weidner, N., Semple, J

doi: 10.1016/j.freeradbiomed.2009.05.032

3.2.4 Oxidative stress reduction Increased oxidative stress causes colonic mucosal barrier activity loss and a marked reduction in TJ proteins, thus enhancing the risk for the development of UC

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Among the ROS, hydroxyl is the most reactive radical, which reacts with lipids, proteins, nucleic acids, and carbohydrates
