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While thymosin alpha-1 promotes immune balance rather than simple stimulation, other peptides with immune-enhancing properties could theoretically worsen lupus by amplifying the already overactive immune response

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This led to the early work of Fong-sen Wu and Terrell Gibbs in my lab (23) showing that progesterone did in fact modulate GABA A and glycine receptors

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Functional assays demonstrated robust CFTR activity in both organoids (via fluid-secretion assays) and monolayers (short-circuit current measurements), and glucose-stimulated insulin release from islets was validated by ELISA
