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This abrupt hormonal withdrawal triggers endometrial shedding (menstruation) and relieves negative feedback at the HPO axis, allowing FSH levels to rise and initiate recruitment of a new follicular cohort, thereby completing the cycle [23]

The reprogramming and differentiation processes can introduce genetic mutations or epigenetic abnormalities, this raises concerns about the safety and long-term effects of iPSC-MSCs in clinical applications

Growing Life cycle Annual Light requirements Full sun Soil Peaty, Well-drained Soil pH 6.1 6.5 (Slightly acidic), 6.6 7.3 (Neutral) Growing habitat Cool temperate regions USDA Plant Hardiness Zones 2a, 2b, 3a, 3b, 4a, 4b, 5a, 5b, 6a, 6b, 7a, 7b, 8a, 8b, 9a, 9b, 10a, 10b, 11a, 11b Planting time Early spring, Fall Plant spacing average 0.3 m (0.98 ft) Growing time 95-100 days Potential insect pests Aphids, Moths, Slugs, Cabbage loopers, Flea beetles, Snails Potential diseases Leaf spot, Black rot, Club root Brussels sprouts are biennials but are usually treated as annuals

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