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2012;7(12, article e51518) doi: 10.1371/journal.pone.0051518

(Pre- and postchelation challenge testing to assess excretion of both toxic and essential elements is discussed below)

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Although the precise mechanisms underlying KDs effects in PD remain incompletely understood, evidence suggests that the diet can modulate glucose utilization in the brain, neurotransmitter metabolism, insulin signaling, oxidative stress, neuroinflammation, and ion channel activity, particularly potassium channels [20]

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