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So, GRd functions by raising the concentration of GSH, which is required for the maintenance of oxide-redox conditions in a living organism
Depending on the type of tumor cells and the surrounding environment, oxidative cell death can occur in various forms
Importantly, under cellular and in vivo conditions, DSePA was shown to induce the mRNA and activity levels of seleno-GPxs [85]
doi: 10.1124/jpet.102.040220
