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Much of the hydrogen peroxide that is produced during oxidative cellular metabolism comes from the breakdown of one of the most damaging ROS, namely the superoxide anion radical (O 2 - )

Thats why its a must to focus on healing the whole human body with a combination of modalities not just one aspect like nutrition

However, its use in GBM chemotherapy is limited by the high resistance of GBM cells to dFdCs (Liu et al., 2012)

This phase establishes whether the drug is safe enough to proceed to efficacy testing, operating under the core ethical principle of nonmaleficence to minimize potential harm to human subjects

10.3390/plants13091266 69 KimC