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Phospho-protein kinase B (phospho-AKT) (Cat #9271), phospho-ribosomal protein S6 (phopho-RPS6K1) (Cat# #2215), and Glycerinaldehyde-3-phosphate-Dehydrogenase (GAPDH) (Cat #4691) were purchased from Cell Signaling Technologies (Danvers, MA, USA)

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doi: 10.1016/j.jchromb.2016.09.026 80 MaJ.LiH

In hepatocellular cancer, Aminopeptidase N is thought to regulate phosphorylation of Ser31 of BDK, which then increases BDK-mediated phosphorylation and activation of ERK1/2, a modification that is associated with increased hepatocellular carcinoma metastasis

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