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D-serine is an endogenous co-agonist of NMDARs and is required to regulate synaptic plasticity and excitatory transmission in the central nervous system (CNS) (Mothet et al., 2000

doi: 10.2147/NSS.S181365

Levodopa Levodopa (L-Dopa) is the metabolic precursor of dopamine and the primary clinical agent for restoring dopaminergic neurotransmission in the central nervous system [213,214]

Cortical iron reflects severity of Alzheimer's disease