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Additionally, studies have shown that fatty acids produced by gut microbes, especially unsaturated fatty acids, are closely associated with the inflammatory state of IBD [12, 13]

Not only is GSH regulated by Nrf2, the thioredoxin-based antioxidant system (TXN1, TXNRD1) is also regulated by Nrf2, indicating that Nrf2 regulates the redox state of proteins (Reisman et al., 2009)

[PubMed: 18832345] 769

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This clear distinction is indicated on the labels of research chemicals, exempting them from specific regulations under Title 21, Parts 100-740 of the Code of Federal Regulations (21CFR)
