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In humans, hydroxyphenylpyruvate dioxygenase-like protein (HPLD) converts 4-HPP to 4-hydroxymandelate (4-HMA) [41]

doi: 10.1016/j.cois.2025.101458 265 SamuelCE
6 Insulin-like growth factor I exerts growth hormone- and insulin-like actions on human muscle protein metabolism. Physiology.org

Protein carbonyl groups content as a useful clinical marker of antioxidant barrier impairment in plasma of children with juvenile chronic arthritis

A study has shown that taking MSM supplements can reduce pain, joint swelling and stiffness compared to participants in the placebo group
