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This depletion correlates directly with elevated ventricular lactate levels, providing concrete biological evidence that the brains of these patients are trapped in a state of high oxidative stress and inefficient anaerobic metabolism

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[6] Zhang Liangyu, Li Qiyan, Li Jingjing, et al

[DOI] [PMC free article] [PubMed] [Google Scholar] 72.Williams C.D., Stengel J., Asike M.I., Torres D.M., Shaw J., Contreras M., Landt C.L., Harrison S.A

Post hoc comparisons showed elevated GSH levels in the participants with current depression (Figure 2), which were significantly increased in comparison to GSH levels in the controls ( p = 0.034) and participants with past depression ( p = 0.013)