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3.1.1.3) is an 84 kDa cytoplasmic protein with demonstrated activity against a wide variety of substrates including TAG, DAG, cholesteryl esters (CEs), and retinyl esters (51)

[ref] Compound heterozygous: MTHFR C677T + A1298C: Having one copy of each variant, called compound heterozygous , reduces enzyme function by around 50%