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Whereas IRP1 with coordinated FeS cluster functions as aconitase, iron deficiency activates the mRNA binding activity of IRP1
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These techniques converge on antioxidative, proangiogenic, and antifibrotic mechanisms, offering promising cellfree alternatives to stem cell transplantation, though evidence remains predominantly preclinical
10.1126/science.1133427 201 SlamenovaD.KozicsK.HunakovaL.MelusovaM.NavarovaJ.HorvathovaE
