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FDA currently lists BPC-157 among compounding substances for which it has identified potential immunogenicity, peptide-impurity, and API-characterization concerns, while noting that it has limited safety information for proposed routes of administration

Compared to young MuSCs, fewer aged MuSCs are found in quiescence, due to either elevated activation or entering a pre-senescent state 5,6

Vitamin b1, b6, and b12 injection needs to be stored in specific temperature

No large-scale human trials exist, meaning the full safety profile in human populations is not yet established

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