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The cellular ATP level was determined by using an ATLP bioluminescence assay kit (SigmaAldrich, USA) in accordance with the manufacturers instructions

Nanomaterials 11(10):2525

Issued:01/2024 PRINCIPAL DISPLAY PANEL NDC 71930-019-12 Hydrocodone Bitartrate and Acetaminophen tablets, USP 5mg/325mg 100 Tablets Rx Only PRINCIPAL DISPLAY PANEL NDC 71930-019-52 Hydrocodone Bitartrate and Acetaminophen tablets, USP 5mg/325mg 500 Tablets Rx Only PRINCIPAL DISPLAY PANEL NDC 71930-019-13 Hydrocodone Bitartrate and Acetaminophen tablets, USP 5mg/325mg 1000 Tablets Rx Only PRINCIPAL DISPLAY PANEL NDC 71930-020-12 Hydrocodone Bitartrate and Acetaminophen Tablets, USP 7.5mg/325mg 100 Tablets Rx Only PRINCIPAL DISPLAY PANEL NDC 71930-020-52 Hydrocodone Bitartrate and Acetaminophen Tablets, USP 7.5mg/325mg 500 Tablets Rx Only PRINCIPAL DISPLAY PANEL NDC 71930-020-13 Hydrocodone Bitartrate and Acetaminophen Tablets, USP 7.5mg/325mg 1000 Tablets Rx Only PRINCIPAL DISPLAY PANEL NDC 71930-021-12 Hydrocodone Bitartrate and Acetaminophen Tablets, USP 10mg/325mg 100 Tablets Rx Only PRINCIPAL DISPLAY PANEL NDC 71930-021-52 Hydrocodone Bitartrate and Acetaminophen Tablets, USP 10mg/325mg 500 Tablets Rx Only PRINCIPAL DISPLAY PANEL NDC 71930-021-13 Hydrocodone Bitartrate and Acetaminophen Tablets, USP 10mg/325mg 1000 Tablets Rx Only

Exposure to the drug induced a mitochondria-independent mode of cell death due to the induction of reactive oxygen species (ROS) through erastin-mediated activation of nicotinamide adenine dinucleotide phosphate (NADPH) oxidase