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Annu Rev Pharmacol Toxicol 47:14383, PMID: 17029566 Kaludercic N, Takimoto E, Nagayama T, Feng N, Lai EW, Bedja D, Chen K, Gabrielson KL, Blakely RD, Shih JC, Pacak K, Kass DA, Di Lisa F, Paolocci N (2010) Monoamine oxidase A-mediated enhanced catabolism of norepinephrine contributes to adverse remodeling and pump failure in hearts with pressure overload

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Xia YJ, Xia H, Chen L, Ying QS, Yu X, Li LH, et al

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The study reveals that enhanced GHR expression leads to increased sensitivity to growth hormone signaling, promoting fibroblast proliferation, collagen synthesis, and extracellular matrix production