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Proteins oxidatively modified by TBI Remarkable efforts have been invested into the discovery of biomarkers of specific neurological disorders

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However, an earlier study using the intragastric ethanol-feeding model failed to show any protection by betaine feeding in the ethanol-induced up-regulation of CD14 and TNF- expression (189)

Homeostatic regulation of GSH levels Glutathione peroxidase (GPx), glutathione reductase (GR), glutathione S-transferase (GST), and glucose-6-phosphate dehydrogenase (G6PD) are responsible for recycling of oxidized glutathione (GSSG) back to reduced glutathione (GSH)

Immunoblotting analysis showed that the protein levels of FOXO3a, AMPK, and phosphorylated Beclin1 (pBeclin1) but not Beclin1 were upregulated after co-treatment (Fig
