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It works from the inside out by influencing biological pathways

Further investigations identified the hepatic rat enzyme with GST B (nowadays called RnoGST A1-1) and it was furthermore found that purified human hepatic GSTs from the Jakoby laboratory displayed even higher specific activity than the rat enzyme ( In retrospect, it is clear that the ketosteroid isomerase activity of the GST in human liver ( 1 B 1 and B 1 B 2 in Stockman et al., 1985)

(2) high risk: cancer, including patients with previous history of cancer

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