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TMAO alters how cholesterol is metabolized so less is eliminated from the body, allowing more cholesterol to deposit and harden into the artery walls (atherosclerosis)

J Liver Res Disord Ther 2:5864

Questo processo particolarmente importante durante l'esercizio fisico , quando l'organismo ha bisogno di una maggiore quantit di energia per supportare l'attivit muscolare

No clinically relevant differences in elvitegravir or cobicistat pharmacokinetics were observed between subjects with moderate hepatic impairment and healthy subjects [see Use In Specific Populations ]
