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Nov 2000;53(5):561-8

Harrist A, Beech RD, King SL, Zanardi A, Cleary MA, Caldarone BJ, et al

When activated, the mast cells in the skin release mediators (histamines, tryptase, TNF-alpha, CXCL9, etc.) that cause inflammation, flushing, itching, or burning.[ref] Related article: Rosacea, underlying causes, genetic susceptibility Dermatographism and mast cell activation syndrome: In a survey of mast cell activation syndrome, dermatographism was found in 89% of the patients.[ref] Dermatographism is when you get welts or raised red lines when you scratch your skin lightly

Personalized Medicine and Tailored Therapies Another area of growth is personalized medicine

Oncol Lett 14(3):31033109 Jo DH et al (2014) Anti-angiogenic effect of bare titanium dioxide nanoparticles on pathologic neovascularization without unbearable toxicity