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Certain genetic variations can reduce the efficiency of this enzyme

[DOI] [PMC free article] [PubMed] [Google Scholar] 123.Ramirez-Nio A.M., DSouza M.S., Markou A
Studies highlighted the crucial importance of various nutrients such as anti-inflammatory nutrientsfor example, vitamin D, antioxidants, mono- and polyunsaturated fatty acids, magnesium, and zincto reduce thyroid inflammation [27]

Water-soluble antioxidants (GSH, vitamin C) are active in the cytosol and plasma, while lipid-soluble antioxidants (vitamin E, carotenoids) localize to membranes (20)

Current models suggest that transformed/proliferative tissue undergoes metabolic reprogramming that results in enhanced glycolytic flux 10,11,12,13,14