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& Farmakis, D

Goldberg TE, Chen C, Wang Y, Jung E, Swanson A, Ing C, et al

In Arabidopsis , KAKTUS ( KAK ) encodes a HECT-type E3 ubiquitin ligase that negatively regulates endoreduplication cycles in trichome branching by accelerating GL3 and EGL3 degradation (El Refy et al., 2004)
Mild reactions are common: rash, nausea, headache
Wang et al., 2008, 2014