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While an inflammatory response is a protective mechanism, unaddressed chronic inflammation can be harmful, making it an underlying mechanism of action for neuropathology

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While cortisone is highly effective at quickly reducing inflammation and pain, it can cause issues with long-term use, such as tissue atrophy, weakened tendons, and blood sugar elevation

Moreover, branched-chain amino acids (BCAAs), popular amongst bodybuilders, may further exacerbate this process by stimulating mTOR pathways that sensitise follicles to androgens